The Panthers play their home games at Ratliff Stadium.
| AUGUST |
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| 27 | EP Pebble Hills | Home | 7:30 |
| SEPTEMBER |
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| 03 | Waco Midway | Away | 7:30 |
| 10 | Amarillo Tascosa | Home | 7:30 |
| 17 | UANL Mexico | Home | 7:30 |
| 24 | Abilene High* | Home | 7:00 |
| OCTOBER |
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| 01 | Wolfforth Frenship* | Away | 7:00 |
| 08 | Odessa High* | Home | 7:00 |
| 15 | Midland High* | Away | 7:00 |
| 22 | San Angelo Central* | Home | 7:00 |
| NOVEMBER |
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| 05 | Midland Lee* | Away | 7:00 |
| 12 | Bi-District Playoff | – | – |
| 19 | State Area Round | – | – |
All District 2-6A Schedules
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